Selected Publications

Rivera M, Zhang H, Pham J, Isquith J, Zhou Q, Sasik R, Mark A, Ma W, Holm F, Fisch K, Kuo D, Jamieson C, Jiang Q. ADAR1 drives stemness of leukemia initiating cells in T-cell acute lymphoblastic leukemia via attenuating immunogenic dsRNA sensing. Cell Reports, 2024. Jan 23;43(2):113704. PMID: 38265938. https://www.cell.com/cell-reports/fulltext/S2211-1247(24)00032-9

Enlund S, Sinha I, Neofytou C, Amor AR, Papadakis K, Nilsson A, Jiang Q, Hermanson O, and Holm F. The CNS Microenvironment Promotes Leukemia Cell Survival by Disrupting Tumor Suppression and Cell Cycle Regulation in Pediatric T-cell Acute Lymphoblastic Leukemia. Experimental Cell Research. https://pubmed.ncbi.nlm.nih.gov/38561062/

Enlund S, Sinha I, Amor AR, Fard S, Tamm E, Jiang Q, Lundin V, Nilsson A, Holm F. Malignant DFFB isoform switching promotes leukemia survival in relapse pediatric T-cell acute lymphoblastic leukemia. eJHaem. 2023; 4:115-124. https://doi.org/10.1002/jha2.634. https://pubmed.ncbi.nlm.nih.gov/36819185/

Crews L, Ma W, Ladel L, Pham J, Balaian L, Steel K, Mondala P, Diep R, Wu C, Mason C, van der Werf I, Oliver I, Reynoso E, Pineda G, Whisenant T, Wentworth P, La Clair J, Jiang Q, Burkart M, and Jamieson C. Reversal of malignant ADAR1 splice isoform switching with Rebecsinib. Cell Stem Cell, 2023 Mar 2;30(3):250-263. PMCID: PMC10134781. https://pubmed.ncbi.nlm.nih.gov/36803553/

Jiang Q, Isquith J, Ladel L, Mark A, Holm F, Mason C, He Y, Mondala Phoebe, Oliver I, Pham J, Ma W, Reynoso E, Ali S, Morris Isabella, Diep R, Nasamran C, Xu G, Sasik R, Rosenthal S, Birmingham A, Coso S, Pineda G, Crews L, Donohoe M, Venter J, Whisenant T, Mesa R, Alexandrov L, Fisch K, Jamieson CH. Inflammation-driven deaminase deregulation fuels human pre-leukemia stem cell evolution. Cell Reports. 2021 Jan 26; 34 (4), 108670. PMCID: 33503434. https://pubmed.ncbi.nlm.nih.gov/33503434/

Jiang Q, Isquith J, Zipeto MA, Diep R, Pham J, Santos ND, Reymoso E, Chau J, Leu H, Lazzari E, Melese E, Ma W, Fang R, Minden M, Morris S, Ren B, Pineda G, Holm F, Jamieson CH. Hyper-editing of cell cycle regulatory and tumor suppressor RNA promotes malignant progenitor propagation. Cancer Cell. 2019; 35, 1-4. https://pubmed.ncbi.nlm.nih.gov/30612940/